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不同化學結構肌松藥對骨骼肌成人型和胎兒型乙酰膽堿受體的作用

趙雪蓮 凌濱 張瑩

注:NMB=神經肌肉阻滯藥;ε-nAChR組和γ-nAChR組相比較,*P<0.05;ε-nAChR組和γ-nAChR組組內比較,#P<0.05;ε-nAChR組和γ-nAChR組相比較,**P<0.01;ε-nAChR組和γ-nAChR組組內比較,##P<0.01 羅庫溴銨對ε-nAChR50%抑制濃度(IC50)明顯大于對γ-nAChR作用的IC50,P<0.001;維庫溴銨抑制ε-nAChR的IC50值顯著小于對γ-nAChR的IC50值,P<0.05;阿曲庫銨抑制ε-nAChR的IC50值顯著小于對γ-nAChR的IC50值,P<0.05。

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